Besides, under the hypercholesterolemia condition, the colonization of Lactobacillus plantarum in rats has been shown to reduce TC, TG, LDL-C, alanine aminotransferase (ALT), aspartate aminotransferase (AST), very-low-density lipoprotein, and atherosclerotic index in the serum (13). This evidence concerns the gene GPT and familial hypercholesterolemia.