GPT and heavy chain disease: As compared to the HCD group, the ALT (1 × 104 CFU/mL group: 27.405 ± 1.340 U/g prot; 1 × 105 CFU/mL group: 19.764 ± 0.889 U/g prot; 1 × 106 CFU/mL group: 16.508 ± 1.289 U/g prot) and AST (1 × 105 CFU/mL group: 45.659 ± 2.560 U/g prot; 1 × 106 CFU/mL group: 43.881 ± 2.971 U/g prot) activities of zebrafish larvae in L. fermentum E15 group were significantly decreased (p < 0.05), suggesting that L. fermentum E15 can ameliorate lipid metabolic disorder and liver function abnormalities (Figures 3E,F).