At the same time, Wu et al. (2023a) by establishing a model of diabetes nephropathy (DKD) and extracting PAA from Wolfiporia cocos, found that PAA can significantly reduce the levels of blood sugar and urinary protein in mice, control renal fibrosis, and downregulate FUNDC1 to promote mitosis, thus having a beneficial impact on the damage of capsular cells in DKD and effectively alleviating renal damage. This evidence concerns the gene FUNDC1 and diabetic kidney disease.