JUN and melanoma: Inhibition of cJun has been shown to suppress the growth of SK‐MEL‐28 malignant melanoma cells and was, therefore, used here to test peptide efficacy in cellular assays.[10, 21] Due to the size and charge of FAM‐HW33, a cell penetrating peptide (CPP) comprised of residues 48–57 of the HIV‐1 TAT protein[22] and a nuclear localization signal (NLS) from the SV40 large T‐cell antigen[23] were appended to the C‐terminus of the molecule (NLSTAT: PKKKRKVYGRKKRRQRRR) to produce FAM‐HW33‐NLSTAT for use in cell‐based assays (Figure S18, Supporting Information).