Age, BMI, HGB, Serum ALB, Serum CEA, CONUT score, tumor size, pT stage, pN stage, nerve invasion, vascular invasion, tumor differentiation, and postoperative chemotherapy were the factors that influenced the prognosis of GC, according to the Cox's univariate analysis (P < 0.05 for all). The gene discussed is CEACAM5; the disease is neoplasm.