PRL and breast cancer: The results revealed that DMBA-induced breast cancer showed a significant increase in steroid hormones, in which PRL was increased by 41% and E2 by 193% compared to the control group, but Amygdalin in co-administration with tamoxifen improved steroid hormones by PRL which decreased by 13% compared to DMBA group, as well as E2 decreased by 15% with Amygdalin as a protective administration in compared to DMBA group, Table 3.