TP53 and neoplasm: B lymphoma cell 2 (BcL-2) which is an anti-apoptotic marker; caspase-3, which is an apoptotic marker; and 53 K. Dalton Protein (P53), which acts as a tumor suppressor and regulates cell division by keeping cells from growing and dividing (proliferating) too fast or in an uncontrolled way66.