Previously, we used machine learning to identify significant fall risk factors in functionally independent elderly and nonelderly individuals with type 2 diabetes as grip strength, fasting serum C-peptide level, knee extension muscle strength, ankle dorsiflexor muscle strength, and proliferative diabetic retinopathy; however, insulin and sulfonylurea treatments were not identified as significant fall risk factors12. This evidence concerns the gene INS and type 2 diabetes mellitus.