SYK and fibrosarcoma: We pretreated amoeba cells with CK-666 (Arp2/3 complex inhibitor), wortmannin (phosphoinositide 3-kinase inhibitor), piceatannol (tyrosine-protein kinase Syk inhibitor), and PP2 (tyrosine-protein kinase Src inhibitor) and incubated them with the fibrosarcoma cells for 3 hours.