We also aimed to determine the contribution of the canonical adiponectin receptors AdipoR1 and AdipoR2 to IA pathology, and thus infected neutrophil-depleted WT, Adipoq-/-, AdipoR1-/- and AdipoR2-/- mice to compare mortality, pathology, fungal burden, inflammatory cell recruitment and cytokine production at day 3 post-infection (Fig 1A). The gene discussed is ADIPOR1; the disease is infection.