In patients with adolescent idiopathic scoliosis, Hui et al. identified differential miRNA-17 expression in bone marrow-derived Mesenchymal Stem Cells (MSCs), while Ganau et al. highlighted the role of TNF-α in inflammatory spinal pathology associated with lumbar synovial cysts [26,27]. Here, TNF is linked to adolescent idiopathic scoliosis.