Kishazi et al. reported a significant elevation in IL-10, IL-12p70, IL-6, IL-13 and TNF-α in GD TAO patients compared to the control group, and L-10, IL-12p70 and IL-8 levels were significantly elevated in TAO regardless of the activity of the disease (CAS). The gene discussed is CXCL8; the disease is thromboangiitis obliterans.