Extensive research has been conducted on the role of METTL16 in regulating cancer progression through m6A modification of target genes, including U6 snRNA [34], MALAT1 [35], XIST [36], and RAB11B‐AS1 [24], and mRNA (MAT2A [37], VPS33B [37], FGFR4 [32], and GPX4 [25]). The gene discussed is XIST; the disease is cancer.