Participants did not show relevant differences in their periodontal status parameters on the basis of gender, which also confirmed our working hypothesis, while one study showed significantly higher values for inflammatory markers (e.g., leukocytes, neutrophil counts, C-reactive protein) in male AD patients [72], neither this nor other related studies showed sex-based differences in the periodontal status indicators assessed. The gene discussed is CRP; the disease is Alzheimer disease.