For D/T group:Any grade: Pyrexia (68%), headache (48%), vomiting/diarrhea (34%/29%), fatigue 32%), dry skin/rash (26%/19%)Grade ≥3: Pyrexia (8%), weight gain (7%), neutropenia (10%), increased ALT (5%). The gene discussed is GPT; the disease is Decreased total neutrophil count.