We found that many of the publications identified did not report on a number of outcomes of interest, exemplifying the current lack of reported information surrounding, for example, the complementary use of anticoagulants and antifibrinolytics during the perioperative period, in addition to the use of postoperative physical therapy, for people with hemophilia A without FVIII inhibitors undergoing major surgery. This evidence concerns the gene F8 and hemophilia A.