By stroke subtypes, TET2 was strongly associated with small vessel stroke (SVS) (OR = 1.29, P = 0.01), weakly associated with large artery stroke (LAS) (OR = 1.21, P = 0.06), and not with cardioembolic stroke (Figure 2; Tables S3 and S6, Supporting Information). Here, TET2 is linked to small vessel stroke.