Notably, although previous studies reported that ZNF217 is implicated in m6A RNA methylation by either sequestering the m6A "writer" METTL3 or enhancing the transcription of the m6A "eraser" FTO 40-45, our findings suggest that ZNF217 is not associated with m6A modification in B-ALL. This evidence concerns the gene METTL3 and precursor B-cell acute lymphoblastic leukemia.