MAP1LC3A and familial pancreatic carcinoma: Therefore, Ad-mCherry-GFP-LC3 transfection results revealed a significant increase in the number of red/yellow (mCherry merged with green) dots in the UTMD group compared to the Control group (57.2 ± 29.5 vs. 11.0 ± 3.3, P < 0.05), suggesting that UTMD treatment significantly increased the number of autophagosomes in pancreatic cancer cells and that autophagic flux remained unobstructed (Figure 4A).