In the first experiment, serum cytokine analysis revealed no differences among groups in terms of IL-6 (normal: 12.15±9.73 pg/ml, DKD: 12.56±18.75 pg/ml, low-dose: 13.32±12.01 pg/ml, intermediate-dose: 25.43±21.27 pg/ml, high-dose: 5.34±10.34 pg/ml) (Fig. 2A) or IL-10 levels (normal: 11.70±6.77 pg/ml, DKD: 12.21±6.77 pg/ml, low-dose: 25.90±10.94 pg/ml, intermediate-dose: 16.94±12.01 pg/ml, high-dose: 14.68±18.80 pg/ml) (Fig. 2B). This evidence concerns the gene IL6 and diabetic kidney disease.