14 thyroid cancer-related genes (AKT1, BRAF, CTNNB1, EIF1AX, HRAS, KRAS, NRAS, PAX8, PIK3CA, PTEN, RET, TERT, THADA, and TP53) and 21 types of gene rearrangements occurring in thyroid cancer (ACBD5, AFAP1L2, ALK, ATG10, BRAF, CALM2, CCDC6, ERC1, ETV6, FLNC, FMNL2, KIAA1217, KIAA1594, KIF20B, NCOA4, NTRK3, PAK1, PAX8, PIBF1, PPAR γ, PXK, RALGAPA2, RET, SND1, and STRN). This evidence concerns the gene PIK3CA and thyroid cancer.