PLOD1 and mucopolysaccharidosis: In addition, compared with HRT or SSRIs alone, the combined use of western medicine and Xiangshao granules can reduce LH levels in MPS patients (SMD=-1.18, 95%CI[-2.05,-0.30], P<0.05) (SMD=-1.09, 95%CI[-1.59, -0.59].