UTP3 and B-cell non-Hodgkin lymphoma: Kang and colleagues report that the blockade of Crlz-1 nuclear movement by AKRAIT as its nuclear localization signal peptide causes the failure of Crlz-1-Runx/CBFβ-Bcl-6 axis cascade and thus the peptide has a significant anti-proliferative and anti-tumor efficacy against the germinal center-derived B cell lymphoma.