A large diversity offusion oncogenes was observed, primarily in one tumor, the three most commonbeing: EWSR1::Fli1 (n = 13) observed in Ewing sarcomas, PAX3::FOXO1 (n = 12) inrhabdomyosarcomas, and ETV6::RUNX1 (n = 8) in childhood leukemias. The gene discussed is EWSR1; the disease is Ewing sarcoma.