TP53 and breast carcinoma: The co-targets were analyzed by GO and KEGG enrichment, and the results showed that the main biological processes of DHIE affecting breast cancer were mitotic cell cycle phase transition, acting on cellular components such as spindle, regulating molecular functions such as protein serine kinase activity and other molecular functions, regulate cell cycle and p53 signaling pathway and other signaling pathways (Figures 4B, C).