SLC22A12 and hyperuricemia: Research has identified various single nucleotide polymorphisms (SNPs) in the SLC2A9 and SLC22A12 gene that are associated with an increased risk of hyperuricaemia and gout, such as G/A genotype for rs3733591 in the SLC2A9 gene and a C/C genotype for rs893006 in the SLC22A12 gene.