The findings revealed a notable increase in the expression of multiple pathways within the high-risk cohort, including IL-17 Signaling Pathway, Staphylococcus Aureus Infection, Motor Proteins, Cell Cycle, and Fructose and Mannose Metabolism (adjusted p-value < 0.05, Figure 8a). The gene discussed is IL17A; the disease is staphylococcus aureus infection.