LAPTM4B and acute lymphoblastic leukemia: However, none study was performed in ALL, so we focused on ALL, particularly Ph+ B-ALL, to elucidate and clarify the biological functional characteristics of LAPTM4B. Taking the advantages of single-cell sequencing and open public data, we found that LAPTM4B was expressed mainly in normal HSCs, progenitors, and AML cells (Figures 6A, B).