While CYP2C19*2 rs4244285 possessed a significantly decreased risk (OR: 0.53, 95% CI: 0.33-0.85 P 0.009) of CC in the studied ruralpopulation, the CYP1B1*3 rs1056836 (Leu4326Val) polymorphism showed a significantly raised risk (OR = 3.28; 95% CI: 2.18-4.94; P 0.0001).A study found that the rs10244285 SNP of CYP2C19*2 lowers the risk of cancer in the group that was looked at, while the rs1056836 SNP ofCYP1B1*3 raises the risk of cancer [39]. The gene discussed is CYP1B1; the disease is cancer.