Moreover, the study found that miR-130a-3p can directly target and inhibit TBL1XR1, which considerably increases the expression of E-cadherin in MGC-803 cells, decreases the expression of N-cadherin in MGC-2 cells and MGC-803 cells, and inhibits EMT, thus suppressing the motility and invasiveness of cancer cells and preventing tumor metastasis16. Here, TBL1XR1 is linked to neoplasm.