Our results demonstrated the promising predictive value of CCL4, CXCL8, and MIF for the CRT response in patients with ESCC (CCL4, AUC=0.675, Figure 1f; CXCL8, AUC=0.699, Figure 1g; MIF, AUC=0.653, Figure 1h). Here, CCL4 is linked to esophageal squamous cell carcinoma.