5 weeks after cell inoculation, the nude mice were sacrificed, and the tumors were peeled off and photographed (Figure 3C); immunohistochemical staining of xenograft tumor tissues revealed that the expression of Ki-67 and PCNA proteins in the CKS2-knockdown cohort was reduced compared with the control group (Figure 3D). The gene discussed is CKS2; the disease is neoplasm.