CTLA4 and lung cancer: Also, Adam et al. [ 28] stated that there was no relationship between patients’ age and sex and CTLA4 expression in lung cancer.In our study, CTLA4 expression levels were 25% higher in those aged 50 and older than in those younger than 50 yearsof age; furthermore, CTLA4 expression was substantially increased in men compared to women, but the correlation was not significant.