HMGN2 and glioblastoma: To analyze the function of HMGN2 in GBM, LN229 and U-87 MG cells were chosen for HMGN2 knockdown using shRNAs (shHMGN2#1, shHMGN2#2, and shHMGN2#3), due to their higher HMGN2 expression levels.