A similar effect of HMGN2 on cell viability, apoptosis, and cell cycle distribution was observed in the HMGN2 overexpression group in LN229 and U-87 MG cells (Fig. 3A–C; Fig. S2J), supporting the notion that HMGN2 exerts a pro-proliferative effect on GBM cells. Here, HMGN2 is linked to glioblastoma.