KEGG pathway analysis of differentially expressed genes between Ythdf1−/− mice and WT mice indicated enrichment in IL-17 signaling, Th1/Th2 cell differentiation, and Th17 cell differentiation (Fig. 5C), suggesting that YTHDF1 deficiency affects the T cell function in ConA-induced hepatitis. The gene discussed is IL17A; the disease is hepatitis A virus infection.