To confirm the diagnosis of her skin eruption, a skin biopsy of the affected area revealed septal panniculitis without vasculitis, consistent with EN (Figure 1B). The laboratory findings reveal notable abnormalities, including an elevated white blood cell count (10.3 × 103/μl), thrombocytosis (542 × 103/μl), elevated lactate dehydrogenase (LDH) (179 U/l), and significantly increased C-reactive protein (CRP) (24.37 mg/dl). The gene discussed is CRP; the disease is panniculitis.