FOXA1 and renal fibrosis: We utilized conditional HNF3α knockout mice and intravenous injection of plasmids that overexpressed Hnf3α to alter HNF3α expression in mouse kidney tissues, constructed an IRI‐induced renal fibrosis model, and evaluated collagen fiber deposition, fibrosis‐related molecules, and inflammatory cytokines to determine the effect of HNF3α on renal fibrosis.