The study findings (Figure 4) demonstrate that compared to oral metformin alone, acupuncture and its combined therapies (SMD = −0.58, 95% CI = −0.77 to −0.39, p < 0.01, I2 = 80%) can significantly reduce LH/FSH levels in PCOS patients. Here, PLOD1 is linked to polycystic ovary syndrome.