NRAS and leukemia: It's worth mentioning that the absence of RAB27B can inhibit the PM localization of NRAS, and that it significantly impedes the development of leukemia induced by Nras mutations in mice.[41] Unlike GOLGA7, RAB27B interacts with ZDHHC9 and modulates ZDHHC9‐mediated NRAS palmitoylation, and RAB27B KO diminishes the level of NRAS palmitoylation.