NRAS and leukemia: As previously reported, palmitoylation is an essential process for NRASG12D leukemogenesis, the C181S mutation inhibited the palmitoylation of oncogenic NRAS and prevented the progression of leukemia.[24, 25] Since BM cells are relatively small, making it difficult to distinguish subcellular localization, we transduced HeLa cells with lentiviruses expressing human GFP‐NRASG12D.