Notably, certain TFs such as ZNF761, MESP1, CREB3L1, ZNF350, BHLHA15, ZBTB42, ZNF614, and CUX2 exhibit high expression in cancer compared to normal tissue in a pan‐cancer view (Figure S2, Supporting Information), especially in PRAD compared to normal prostate (Figure S3, Supporting Information). The gene discussed is ZBTB42; the disease is prostate adenocarcinoma.