MFN1 and female infertility: Mitochondria are dynamic organelles that continuously remodel their architecture through fusion and fission, collectively referred to as mitochondrial dynamics, to adapt to changes in the bioenergetic environment.[13] MFN1 and MFN2 are dynamin‐related GTPases essential for mitochondrial fusion in mammalian cells.[14] Deletion of Mfn1 or Mfn2 results in embryonic lethality during midgestation in mice.[15] Notably, depletion of Mfn1, but not Mfn2, in oocytes leads to follicular depletion and female infertility.