PIAS1 and atherosclerosis: The results revealed that circ‐PIAS1‐5 expression in the blood of patients with HHcy‐associated atherosclerosis was lower than that in the blood of healthy controls (Figure 5C); circ‐PIAS1‐5 exhibits a more intimate relationship with Hcy (Table2); and there was no significant difference in circ‐PIAS1‐5 expression between the atherosclerosis without HHcy group and the healthy group (Figure S4, Supporting Information).