To determine how circ‐PIAS1‐5 contributes to the pathogenesis of atherosclerosis as a sponge of miR‐219a‐2‐3p, TEAD1, NEBL, and ZNF83 were identified as potential targets of miR‐219a‐2‐3p via bioinformatics software (miRDB, miRTarBase, and TargetScan databases) (Figure 7A). The gene discussed is PIAS1; the disease is atherosclerosis.