In the multivariate regression model, after adjusting for various factors, such as age, smoking status, race, education, marital status, ALT, AST, GGT, diabetes, hypertension and hypercholesterolemia, the ORs ranged from 1.46 to 4.77, indicating a strong correlation between sUA levels and MAFLD, with consistent results (p < 0.001). Here, GPT is linked to hypertensive disorder.