Vujkovic et al found evidence of two genome-wide significant loci for type 2 diabetes-related CAD in a large-scale GWIS of European participants [28]; the study discovered a new variant near the SORT1 gene (rs602633) and replicated the previous signal in the 9p21 region (rs1831733), which provides greater protection against CAD in individuals with type 2 diabetes than in those without type 2 diabetes. Here, SORT1 is linked to type 2 diabetes mellitus.