In line with this, and besides the classical antigen-dependent immune response mediated by CD8+T cell, we further observed that deficiency in branched N-glycans in Mgat5 KO mice also stimulated increased infiltration of γδ T cells, which was significantly observed at premalignancy, namely in dysplasia stage of KO mice compared to WT mice, with a tendency to increase also in carcinoma (Figure 3H). Here, MGAT5 is linked to carcinoma.