IL17A and carcinoma: This antitumoral phenotype observed in KO mice was further validated by the increased pro-inflammatory microenvironment as demonstrated by the increased expression of pro-inflammatory cytokines, including IFNγ and IL-17 in the colon tissue, showing that Mgat5 KO mice have an increased production of IFNγ in dysplasia and carcinoma (Figure 3J), as well as an increase in IL-17A in dysplasia and a tendency in carcinoma (Figure 3K).