We observed a significant overexpression of Mgat5 glycogene as well as Mgat4a and Mgat3 in LGD, HGD, and carcinoma, when compared with inflamed tissue, suggesting an overall increase in complex N-glycosylation pathway along CAC development (Figure 2A), which is in accordance with our human results (Figure 1). The gene discussed is MGAT5; the disease is carcinoma.