PAPPA and urethra adenocarcinoma: Similar to all women and regardless of the PAPP-A and UAD are plotted versus longitudinal or average size of the fibroid, the fibroid size–PAPP-A data points display a rather better but still weak and non-significant correlation than that of the fibroid size–UAD data points for women with intramural fibroids (Figs. 2B, D).