Notably, PseudoSorter proficiently extracts a subset of neurons in the Tau-only group that exhibit a decrease in spike rates for spikes with an FWHM of approximately 0.27 ms (Fig. 5, B and C), suggesting that Tau has an effect on the network activity stemming either from multiunit activity defects, or from defects in fast inhibitory (60) neurons, the latter of which matches observations from data from patients with AD (61). The gene discussed is MAPT; the disease is Alzheimer disease.