Among the 11 FUT genes identified in humans, Fucosyltransferase 3 and Fucosyltransferase 6 promote cancer cell adhesion and migration via sialyl Lewis antigens and TGF-β-mediated epithelial-mesenchymal transition6, while Fucosyltransferase 4 (FUT4) is implicated in immune regulation and poor prognosis in lung adenocarcinoma patients through its influence on PD-1 expression7. The gene discussed is FUT4; the disease is cancer.