NOXA1 and colorectal cancer: Additionally, ROC and AUC analyses of the TCGA cohort highlighted Noxa1's potential as a standalone prognostic feature, with AUC values of 0.649 at 3 years, 0.565 at 5 years, and 0.510 at 10 years (Figure 3F), reinforcing Noxa1's significance in predicting long-term outcomes in colorectal cancer patients.