INS and cardiovascular disorder: In multivariate analysis, compared with the multimorbidity-free, patients with cardiovascular disease patterns (Class1) had greater BMI (OR [95 % CI]: 2.52 [1.35,4.70]) and LDL (OR [95 % CI]: 1.27 [1.00,1.60]), and were more likely not to be treated with insulin (OR [95 % CI]: 2.19 [1.29,3.73).