KL and schizophrenia: It is also important to mention that, though there are very few relevant Indian studies reported on alteration in the expression of Klotho in schizophrenia in India27 with a few key reviews presented by the same group of authors on the role of Klotho in schizophrenia.26–28 However, to the best of our knowledge, this is the first Asian Indian study to evaluate the influence of the genetic contribution of Klotho on cognitive function in schizophrenia.