TNF and hepatocellular carcinoma: The miR-362-5p sponge inhibited the expression of PD-L1 and CD14 on neutrophils in the livers of DEN/CCl4-induced HCC mice (Figure 7L-M) and restored the function of hepatic CD4+ T cells (Figure 7N, S8D) and CD8+ T cells (Figure 7O, S8E), as indicated by downregulated PD-1 and Tim3 expression and upregulated TNF-α production.